MicroRNA-related sequence variations in human cancers
نویسندگان
چکیده
منابع مشابه
MicroRNA Involvement in Human Cancers.
Featured Article: Yanaihara N, Caplen N, Bowman E, Seike M, Kumamoto K, Yi M, et al. Unique microRNA molecular profiles in lung cancer diagnosis and prognosis. Cancer Cell 2006;9:189 –98. Recent evidence has revealed that microRNAs (miRNAs) function as tumor suppressors and oncogenes, and therefore miRNAs might prove useful in the diagnosis and treatment of cancer. In 2002, Croce’s group report...
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Naturally occurring microRNAs (miRNAs), small non-coding RNAs of 19 to 24 nucleotides (nt), are encoded in the genomes of invertebrates, vertebrates, and plants. miRNAs act as regulators of gene expression during development and differentiation at the transcriptional, posttranscriptional, and/or translational levels, although most target genes are still elusive. Many miRNAs are conserved in seq...
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MicroRNAs (miRNAs) have important roles in all biological pathways in multicellular organisms. Over 1,400 human miRNAs have been identified, and many are conserved among vertebrates and invertebrates. Regulation of miRNA is the most common mode of post-transcriptional gene regulation. The miRNAs that are involved in the initiation and progression of cancers are termed oncomiRs and several of th...
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At present, a full understanding of the mechanisms by which colorectal cancer (CRC) distant metastases form is still beyond our reach because of the intricate regulation of gene expression. MicroRNAs (miRNAs) are shown to be involved in various human diseases including cancers through negative regulation of target gene expression at the post-transcriptional level. However, there are only a few ...
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ژورنال
عنوان ژورنال: Human Genetics
سال: 2013
ISSN: 0340-6717,1432-1203
DOI: 10.1007/s00439-013-1397-x